From basic research to policy
Our main motivation is to reduce inequality in health. We see the gross global differences in mortality as the great moral problem of our times – in line with slavery in the 18th-19th century, hopefully something we will soon look back at with the same disbelief. Our studies are directed towards identifying the major causes of morbidity and mortality and the health interventions that most efficiently can reduce mortality and morbidity.
Our research ahs led to the following policy consequences:
- High-titre measles vaccine was stopped globally after we showed that it was associated with 2-fold increased female mortality – had it not been stopped it would have led to ~500.000 excess female deaths annually.
- BCG is now given to children with low birth weight after we showed….
- Vitamin A is not given to neonates after we showed…
We regularly summarise our findings to WHO’s committee on vaccines (SAGE), with the aim that these findings can be translated into policy. Here is a list of our letters….
- Aaby P, Benn CS. WHO-Letter I: Non-specific beneficial effects of oral polio vaccine (OPV) – September-8-2015
Click here to read SAGE Letter-I.
- Aaby P, Benn CS. WHO-Letter II: RTS,S malaria vaccine and child mortality – October-10-2015
Click here to read SAGE Letter-II.
- Aaby P, Benn CS. WHO-Letter III: RTS,S malaria vaccine and potential sex-differential effects – October-26-2015
Click here to read SAGE Letter-III.
- Aaby P, Benn CS. WHO-Letter IV: RTS,S malaria vaccine: Non-live vaccines are associated with increased female mortality – March-6-2016
Click here to read SAGE Letter-IV.
- Aaby P, Benn CS. WHO-Letter V: The SAGE review of diphtheria-tetanus-pertussis (DTP) vaccine: Follow-up on the potential deleterious non-specific and sex-differential effects of DTP – april-7-2016
Click here to read SAGE Letter-V.
- Benn CS, Fisker AB, Aaby P. SAGE-VI-Non-specific benificial effects of OPV-18-04-2017
Click here to read SAGE Letter-VI.
- Benn CS, Fisker AB, Thysen SM, Aaby P. WHO-Letter VII: The sequence of measles and DTP-containing vaccines has important consequences for overall child mortality – March 24 -2019
Click here to read SAGE Letter-VII.